Abstract
Since its establishment in 2002, the African Union (AU) has led African countries to make remarkable achievements on the road to joint self-improvement, development and revitalization, including in the field of public health governance. The outbreak of the COVID-19 pandemic in 2020 is a major event in the history of public health governance in Africa and the world at large. As the continent with the most concentrated developing countries, the heaviest burden of disease and very weak public health systems, Africa faces serious challenges. Based on the strong recognition of pan-Africanism, the AU has been coordinating the solidarity among African countries to fight against the COVID-19, promoting the development of African public health governance mechanisms, and strengthening legal supervision of public health.